{"id":1432,"date":"2023-01-23T14:46:45","date_gmt":"2023-01-23T12:46:45","guid":{"rendered":"https:\/\/dehems.med.uoa.gr\/pms-epi\/?p=1432"},"modified":"2023-12-05T15:21:50","modified_gmt":"2023-12-05T13:21:50","slug":"systematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/dehems.med.uoa.gr\/pms-epi\/en\/course-category\/2nd-semester\/systematic-review-and-meta-analysis","title":{"rendered":"Systematic Review and Meta-analysis"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\"><strong>Systematic Review and Meta-analysis<\/strong><\/h3>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Learning objectives<\/h4>\n\n\n\n<p>Upon successful completion of the course the post-graduate students are expected to be able to:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>develop a systematic review and meta-analysis protocol according to SPIRIT guidelines<\/li>\n\n\n\n<li>apply methods used in meta-analysis. More specifically, they will be able to:\n<ul class=\"wp-block-list\">\n<li>Choose and apply fixed- and random-effects models based on the characteristics of the data<\/li>\n\n\n\n<li>Apply the <em>Mantel-Heanzel, Peto, Inverse variance, Der Simonian and Laird<\/em> methods.<\/li>\n\n\n\n<li>Apply and interpret the heterogeneity criterion Q and I<sup>2<\/sup><\/li>\n\n\n\n<li>Apply meta-regression and investigate sources of heterogeneity<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>Implement sensitivity analysis<\/li>\n\n\n\n<li>create forest plots, as well as funnel plots, graphs to investigate the systematic error of small studies or to identify studies with a large effect on the results, etc.<\/li>\n\n\n\n<li>understand and evaluate results of meta-analyses. In particular:\n<ul class=\"wp-block-list\">\n<li>heterogeneity<\/li>\n\n\n\n<li>systematic publication error<\/li>\n\n\n\n<li>effect of small studies<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>publish findings of a meta-analysis according to PRISMA guidelines.<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Course content<\/h4>\n\n\n\n<p>The following topics are covered:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Introduction to meta-analysis \u2013Protocol development<\/li>\n\n\n\n<li>Systematic review<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Practical exercise in literature review through PubMed<\/li>\n\n\n\n<li>Study evaluation and data extraction<\/li>\n\n\n\n<li>Synthesis of the estimates of studies &#8211; fixed and random effects model<\/li>\n\n\n\n<li>Systematic errors in meta-analysis<\/li>\n\n\n\n<li>Assessment of heterogeneity<\/li>\n\n\n\n<li>Practical exercise in Revman<\/li>\n\n\n\n<li>Practical exercise in STATA<\/li>\n\n\n\n<li>Evaluation and presentation of findings of a meta-analysis for publication<\/li>\n\n\n\n<li>Practical exercise in STATA<\/li>\n\n\n\n<li>General issues in meta-analysis<\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\"><div class=\"taxonomy-category lessonCategory wp-block-post-terms has-small-font-size\"><span class=\"wp-block-post-terms__prefix\">Category: <\/span><a href=\"https:\/\/dehems.med.uoa.gr\/pms-epi\/en\/category\/course-category\/2nd-semester\" rel=\"tag\">2nd semester<\/a><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-0dfbf163 wp-block-group-is-layout-flex\">\n\n<\/div>\n\n\n\n<div class=\"wp-block-columns are-vertically-aligned-top is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-right is-layout-flex wp-container-core-buttons-is-layout-765c4724 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-font-size is-style-fill has-small-font-size\"><a class=\"wp-block-button__link has-black-color has-cyan-bluish-gray-background-color has-text-color has-background wp-element-button\" href=\"https:\/\/dehems.med.uoa.gr\/pms-epi\/msc-courses\">Return to courses<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Systematic Review and Meta-analysis Learning objectives Upon successful completion of the course the post-graduate students are expected to be able to: Course content The following topics are covered:<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"","disable_featured_image":false,"footnotes":""},"categories":[85],"tags":[],"class_list":["post-1432","post","type-post","status-publish","format-standard","hentry","category-2nd-semester"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - 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